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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ESPL1
All Species:
1.21
Human Site:
T1519
Identified Species:
3.81
UniProt:
Q14674
Number Species:
7
Phosphosite Substitution
Charge Score:
-0.29
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q14674
NP_036423.4
2120
233113
T1519
D
S
A
S
G
G
K
T
P
A
P
G
P
E
A
Chimpanzee
Pan troglodytes
Rhesus Macaque
Macaca mulatta
XP_001103494
2120
233105
A1519
D
S
A
S
G
R
K
A
P
A
P
D
P
E
A
Dog
Lupus familis
XP_849828
2116
232497
A1515
D
S
T
L
D
G
K
A
P
A
P
G
P
D
T
Cat
Felis silvestris
Mouse
Mus musculus
P60330
2118
233016
A1515
D
S
A
S
G
E
K
A
A
A
A
D
T
G
L
Rat
Rattus norvegicus
NP_001164073
2109
231597
A1506
D
S
A
S
G
E
K
A
A
A
A
E
P
G
L
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_423289
1597
172559
K1027
P
K
S
V
C
C
S
K
R
A
L
L
P
R
S
Frog
Xenopus laevis
Zebra Danio
Brachydanio rerio
XP_001337869
2182
240839
T1586
L
R
G
S
D
T
E
T
K
D
T
G
S
P
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_782226
2231
246313
K1617
E
D
T
G
K
K
G
K
R
R
G
R
G
T
R
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
N.A.
95.9
82.3
N.A.
77.3
77.8
N.A.
N.A.
27.1
N.A.
34.6
N.A.
N.A.
N.A.
N.A.
22.4
Protein Similarity:
100
N.A.
97.7
88.2
N.A.
85.4
85.7
N.A.
N.A.
40
N.A.
52.3
N.A.
N.A.
N.A.
N.A.
40.7
P-Site Identity:
100
N.A.
80
60
N.A.
46.6
53.3
N.A.
N.A.
13.3
N.A.
20
N.A.
N.A.
N.A.
N.A.
0
P-Site Similarity:
100
N.A.
80
66.6
N.A.
46.6
53.3
N.A.
N.A.
26.6
N.A.
26.6
N.A.
N.A.
N.A.
N.A.
6.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
50
0
0
0
0
50
25
75
25
0
0
0
25
% A
% Cys:
0
0
0
0
13
13
0
0
0
0
0
0
0
0
0
% C
% Asp:
63
13
0
0
25
0
0
0
0
13
0
25
0
13
13
% D
% Glu:
13
0
0
0
0
25
13
0
0
0
0
13
0
25
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
13
13
50
25
13
0
0
0
13
38
13
25
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
13
0
0
13
13
63
25
13
0
0
0
0
0
0
% K
% Leu:
13
0
0
13
0
0
0
0
0
0
13
13
0
0
25
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% N
% Pro:
13
0
0
0
0
0
0
0
38
0
38
0
63
13
0
% P
% Gln:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Q
% Arg:
0
13
0
0
0
13
0
0
25
13
0
13
0
13
13
% R
% Ser:
0
63
13
63
0
0
13
0
0
0
0
0
13
0
13
% S
% Thr:
0
0
25
0
0
13
0
25
0
0
13
0
13
13
13
% T
% Val:
0
0
0
13
0
0
0
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _